BHOPAL/NEW DELHI: As the number of children dying of renal failure in MP’s Chhindwara district after consumption of cough syrup rose to 11, with two more fatalities reported on Saturday, a laboratory test report of Coldrif — the cough medicine taken by some of the victims — has revealed it contained a poisonous industrial chemical, prompting the state to ban its sale.
The report received by MP government from Tamil Nadu drugs control department on Saturday said the sample tested was “found adulterated, since it contains 48.6% diethylene glycol”. DEG, used in anti-freeze and brake fluids, is known to cause acute kidney failure and death when ingested.
The state government immediately ordered a crackdown on Coldrif, manufactured by TN-based Sresan Pharmaceuticals , with the Food and Drugs Administration issuing urgent instructions to all drug inspectors to seize existing stocks, prevent further sales and draw samples from other batches for testing. The government also extended the prohibition to all other medicines made by the pharma company.
MP CM Mohan Yadav, in an X post, said: “Death of children in Chhindwara caused by Coldrif syrup is extremely painful.” Late Saturday evening, he announced a compensation of Rs 4 lakh for the families of each of the deceased children. The state government would also bear the cost of treatment for the children still under care, Yadav said.
Kids’ cough syrup deaths trigger multi-state checks
The cough-syrup-linked deaths in MP and Rajasthan have sounded alarm bells across the country, with several states announcing probes and taking precautionary measures.
The Central Drug Standards Control Organisation has initiated risk-based inspection of drug manufacturing units in six states — Himachal Pradesh, Uttarakhand, Gujarat, Tamil Nadu, MP and Maharashtra. The inspections are focused on companies manufacturing cough syrups, antipyretics & antibiotics, samples of which were picked up by the drug regulatory authorities from regions from where the fatalities were reported.
The deaths in Chhindwara have taken place over a period of one month. All the kids were aged below five years, and renal failure was reportedly caused after taking cough syrups, including Coldrif, were prescribed by local doctors at private clinics. Five kids are recuperating at Government Medical College & Hospital in Nagpur.
The deaths, first reported in late Aug, were largely concentrated in villages in Parasia tehsil of Chhindwara. The children initially showed symptoms of cold and mild fever, and were treated with cough syrups and routine medicines. However, their condition worsened soon with reduced urine output and acute kidney complications.
Union health ministry sources said a multidisciplinary team comprising experts from the National Institute of Virology , Indian Council of Medical Research , National Environmental Engineering Research Institute, CDSCO and AIIMS-Nagpur, among others, were still analysing various samples and factors to assess the cause of deaths in and around Chhindwara.
The ministry on Friday stated six samples tested by CDSCO and three by MP Food and Drugs Administration were found to be free of DEG and ethylene glycol. On Saturday, ministry sources clarified that the six “samples that have been tested so far by CDSCO were not of the two suspected cough syrups, including Coldrif, that have been under scanner”.
The analysis of the samples of Coldrif and other suspected cough syrup by MP drug authorities is still underway.
The report received by MP government from Tamil Nadu drugs control department on Saturday said the sample tested was “found adulterated, since it contains 48.6% diethylene glycol”. DEG, used in anti-freeze and brake fluids, is known to cause acute kidney failure and death when ingested.
The state government immediately ordered a crackdown on Coldrif, manufactured by TN-based Sresan Pharmaceuticals , with the Food and Drugs Administration issuing urgent instructions to all drug inspectors to seize existing stocks, prevent further sales and draw samples from other batches for testing. The government also extended the prohibition to all other medicines made by the pharma company.
MP CM Mohan Yadav, in an X post, said: “Death of children in Chhindwara caused by Coldrif syrup is extremely painful.” Late Saturday evening, he announced a compensation of Rs 4 lakh for the families of each of the deceased children. The state government would also bear the cost of treatment for the children still under care, Yadav said.
Kids’ cough syrup deaths trigger multi-state checks
The cough-syrup-linked deaths in MP and Rajasthan have sounded alarm bells across the country, with several states announcing probes and taking precautionary measures.
The Central Drug Standards Control Organisation has initiated risk-based inspection of drug manufacturing units in six states — Himachal Pradesh, Uttarakhand, Gujarat, Tamil Nadu, MP and Maharashtra. The inspections are focused on companies manufacturing cough syrups, antipyretics & antibiotics, samples of which were picked up by the drug regulatory authorities from regions from where the fatalities were reported.
The deaths in Chhindwara have taken place over a period of one month. All the kids were aged below five years, and renal failure was reportedly caused after taking cough syrups, including Coldrif, were prescribed by local doctors at private clinics. Five kids are recuperating at Government Medical College & Hospital in Nagpur.
The deaths, first reported in late Aug, were largely concentrated in villages in Parasia tehsil of Chhindwara. The children initially showed symptoms of cold and mild fever, and were treated with cough syrups and routine medicines. However, their condition worsened soon with reduced urine output and acute kidney complications.
Union health ministry sources said a multidisciplinary team comprising experts from the National Institute of Virology , Indian Council of Medical Research , National Environmental Engineering Research Institute, CDSCO and AIIMS-Nagpur, among others, were still analysing various samples and factors to assess the cause of deaths in and around Chhindwara.
The ministry on Friday stated six samples tested by CDSCO and three by MP Food and Drugs Administration were found to be free of DEG and ethylene glycol. On Saturday, ministry sources clarified that the six “samples that have been tested so far by CDSCO were not of the two suspected cough syrups, including Coldrif, that have been under scanner”.
The analysis of the samples of Coldrif and other suspected cough syrup by MP drug authorities is still underway.
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